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PAPSS2 Antibody

Product Specifications

Background

Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes. SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2.

NCBI Gene ID

9060

Swiss Prot

O95340

Accession Number

O95340

Host

Rabbit

Reactivity

Human

Immunogen

This PAPSS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 544-574 amino acids from the C-terminal region of human PAPSS2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

70 kDa

Fragment

Rabbit Ig

Symbol

PAPSS2

NCBI Official Name

Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2

NCBI Organism

Homo sapiens

Background Reference 01

Xu, Z.H., et al., Biochem. Biophys. Res. Commun. 268 (2) :437-444 (2000) .

Background Reference 02

Kurima, K., et al., J. Biol. Chem. 274 (47) :33306-33312 (1999) .

Background Reference 03

Ul Haque, M.F., et al., Nat. Genet. 20 (2) :157-162 (1998) .

Background Reference 04

Kurima, K., et al., Proc. Natl. Acad. Sci. U.S.A. 95 (15) :8681-8685 (1998) .

Other Product Names

Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2, PAPS synthase 2, PAPSS 2, Sulfurylase kinase 2, SK 2, SK2, Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT, Adenylyl-sulfate kinase, 3'-phosphoadenosine-5'-phosphosulfate synthase, APS kinase, Adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenylylsulfate 3'-phosphotransferase, PAPSS2, ATPSK2

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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