PACSIN2 Antibody

Product Specifications

Background

PACSIN may play a role in vesicle formation and transport. This protein homo- and hetero-aggregates with other PACSINs. It also binds dynamin 1, synaptojanin, synapsin 1 and the neural Wiskott-Aldrich syndrome protein (N-WASP) . The protein exhibits a cvesicle-like cytoplasmic distribution and is ubiquitously expressed. PACSIN is phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC) . The protein contains 1 FCH domain and 1 SH3 domain.

NCBI Gene ID

11252

Swiss Prot

Q9UNF0

Accession Number

Q9UNF0

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This PACSIN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-371 amino acids from the C-terminal region of human PACSIN2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

56 kDa

Fragment

Rabbit Ig

Symbol

PACSIN2

NCBI Official Name

Protein kinase C and casein kinase substrate in neurons protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (26) :16899-16903 (2002) . Wiemann, S., et al., Genome Res. 11 (3) :422-435 (2001) . Ritter, B., et al., FEBS Lett. 454 (3) :356-362 (1999) . Dunham, I., et al., Nature 402 (6761) :489-495 (1999) .