GSG2 Antibody
Product Specifications
Background
Post-translational modifications of conserved N-terminal tail residues in histones regulate many aspects of chromosome activity. Mitotic phosphorylation of H3 Thr 3 occurs in prophase and dephosphorylation during anaphase. Haspin, a dual serine/threonine kinase, plays an important role in regulation of chromosome and spindle function during mitosis and meiosis via its function in phosphorylation of the threonine residue in the third position of histone 3 (Thr3) .
NCBI Gene ID
83903
Swiss Prot
Q8TF76
Accession Number
Q8TF76
Host
Rabbit
Reactivity
Human
Immunogen
This Haspin GSG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323~352 amino acids from the central region of human haspin.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
88 kDa
Fragment
Rabbit Ig
Symbol
GSG2
NCBI Official Name
Serine/threonine-protein kinase haspin
NCBI Organism
Homo sapiens
Background Reference 01
Dai, Jun et al. Genes Dev 19:472-88 (2005) .
Background Reference 02
Higgins, J.M., Gene 267 (1) :55-69 (2001) .
Background Reference 03
Tanaka, H., et al., Mol. Hum. Reprod. 7 (3) :211-218 (2001) .
Other Product Names
Serine/threonine-protein kinase haspin, Germ cell-specific gene 2 protein, H-haspin, Haploid germ cell-specific nuclear protein kinase, GSG2
Tested Applications
WB, IHC-P
Protein ID
296439330
Physical Properties
Liquid
Curated Selection
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