TRPM7 Antibody
Product Specifications
Background
TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.[supplied by OMIM]
NCBI Gene ID
54822
Swiss Prot
Q96QT4
Accession Number
Q96QT4
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This TRPM7 (CHAK1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1821-1850 amino acids from the C-terminal region of human TRPM7 (CHAK1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-368
Calculated Molecular Weight
213 kDa
Fragment
Rabbit Ig
Symbol
TRPM7
NCBI Official Name
Transient receptor potential cation channel subfamily M member 7
NCBI Organism
Homo sapiens
Background Reference 01
Blume-Jensen P, et al. Nature 2001. 411: 355.
Background Reference 02
Cantrell D, J. Cell Sci. 2001. 114: 1439.
Background Reference 03
JhiangOncogene 2000. 19: 5590.
Background Reference 04
Manning G, et al. Science 2002. 298: 1912.
Other Product Names
Transient receptor potential cation channel subfamily M member 7, Channel-kinase 1, Long transient receptor potential channel 7, LTrpC-7, LTrpC7, TRPM7, CHAK1, LTRPC7
Tested Applications
WB, IHC-P
Protein ID
56404941
Physical Properties
Liquid
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