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BRD2 Antibody

Product Specifications

Background

BRD2 is a mitogen-activated kinase which localizes to the nucleus. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3 but sequence comparison suggests that the protein is not involved in the immune response. Homology to the Drosophila gene female sterile homeotic suggests that this human protein may be part of a signal transduction pathway involved in growth control.

NCBI Gene ID

6046

Swiss Prot

P25440

Accession Number

P25440

Host

Rabbit

Reactivity

Human

Immunogen

This BRD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-200 amino acids from the Central region of human BRD2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

88 kDa

Fragment

Rabbit Ig

Symbol

BRD2

NCBI Official Name

Bromodomain-containing protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Pal, D.K., et al., Am. J. Hum. Genet. 73 (2) :261-270 (2003) .

Background Reference 02

Crowley, T.E., et al., Mol. Endocrinol. 16 (8) :1727-1737 (2002) .

Background Reference 03

Denis, G.V., et al., Cell Growth Differ. 11 (8) :417-424 (2000) .

Background Reference 04

Taniguchi, Y., et al., Genomics 51 (1) :114-123 (1998) .

Other Product Names

Bromodomain-containing protein 2, O2711, Really interesting new gene 3 protein, BRD2, KIAA9001, RING3

Tested Applications

WB, IHC-P

Protein ID

12230989

Physical Properties

Liquid

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