PIP5KI gamma Antibody
Product Specifications
Background
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
NCBI Gene ID
23396
Swiss Prot
O60331
Accession Number
O60331
Host
Rabbit
Reactivity
Human
Immunogen
This PIP5KI gamma (PIP5K1G) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-57 amino acids from the N-terminal region of human PIP5KI gamma (PIP5K1G) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
73 kDa
Fragment
Rabbit Ig
Symbol
PIP5K1C
NCBI Official Name
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
NCBI Organism
Homo sapiens
Background Reference 01
Ling, K., et al., Nature 420 (6911) :89-93 (2002) .
Background Reference 02
Di Paolo, G., et al., Nature 420 (6911) :85-89 (2002) .
Background Reference 03
Ishihara, H., et al., J. Biol. Chem. 273 (15) :8741-8748 (1998) .
Other Product Names
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma, PIP5K1-gamma, PtdIns (4) P-5-kinase 1 gamma, Phosphatidylinositol 4-phosphate 5-kinase type I gamma, PIP5KIgamma, PIP5K1C, KIAA0589
Tested Applications
WB, IHC-P
Physical Properties
Liquid
Curated Selection
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