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PIP5KI gamma Antibody

Product Specifications

Background

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

NCBI Gene ID

23396

Swiss Prot

O60331

Accession Number

O60331

Host

Rabbit

Reactivity

Human

Immunogen

This PIP5KI gamma (PIP5K1G) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-57 amino acids from the N-terminal region of human PIP5KI gamma (PIP5K1G) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

73 kDa

Fragment

Rabbit Ig

Symbol

PIP5K1C

NCBI Official Name

Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma

NCBI Organism

Homo sapiens

Background Reference 01

Ling, K., et al., Nature 420 (6911) :89-93 (2002) .

Background Reference 02

Di Paolo, G., et al., Nature 420 (6911) :85-89 (2002) .

Background Reference 03

Ishihara, H., et al., J. Biol. Chem. 273 (15) :8741-8748 (1998) .

Other Product Names

Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma, PIP5K1-gamma, PtdIns (4) P-5-kinase 1 gamma, Phosphatidylinositol 4-phosphate 5-kinase type I gamma, PIP5KIgamma, PIP5K1C, KIAA0589

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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