PI3KR2 Antibody
Product Specifications
Background
PI3KR2 binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.
NCBI Gene ID
5296
Swiss Prot
O00459
Accession Number
O00459
Host
Rabbit
Reactivity
Human
Immunogen
This PI3KR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-298 amino acids from the C-terminal region of human PI3KR2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
82 kDa
Fragment
Rabbit Ig
Symbol
PIK3R2
NCBI Official Name
Phosphatidylinositol 3-kinase regulatory subunit beta
NCBI Organism
Homo sapiens
Background Reference 01
Janssen, J.W., et al., Oncogene 16 (13) :1767-1772 (1998) .
Background Reference 02
Volinia, S., et al., Oncogene 7 (4) :789-793 (1992) .
Background Reference 03
Carpenter, C.L., et al., J. Biol. Chem. 265 (32) :19704-19711 (1990) .
Other Product Names
Phosphatidylinositol 3-kinase regulatory subunit beta, PI3-kinase regulatory subunit beta, PI3K regulatory subunit beta, PtdIns-3-kinase regulatory subunit beta, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, PI3-kinase subunit p85-beta, PtdIns-3-kinase regulatory subunit p85-beta, PIK3R2
Tested Applications
WB, IHC-P
Physical Properties
Liquid
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