PIK3R1 Antibody

Product Specifications

Background

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance.

NCBI Gene ID

5295

Swiss Prot

P27986

Accession Number

P27986

Host

Rabbit

Reactivity

Human

Immunogen

This PIK3R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 558-587 amino acids from human PIK3R1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Immunology, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Xenopus, Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

84 kDa

Fragment

Rabbit Ig

Symbol

PIK3R1

NCBI Official Name

Phosphatidylinositol 3-kinase regulatory subunit alpha

NCBI Organism

Homo sapiens

Background Reference 01

Kobayashi, H., et al., J. Biol. Chem. 279 (8) :6371-6379 (2004) .

Background Reference 02

Liu, H., et al., J. Cell Biol. 164 (4) :603-612 (2004) .

Background Reference 03

Sun, M., et al., J. Biol. Chem. 278 (44) :42992-43000 (2003) .

Background Reference 04

Khan, N.A., et al., J. Neurovirol. 9 (6) :584-593 (2003) .

Other Product Names

Phosphatidylinositol 3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha, PIK3R1, GRB1