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PI3KCD Antibody

Product Specifications

Background

Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. See MIM 602838. The class I PI3Ks display a broad phosphoinositide lipid substrate specificity and include p110-alpha , p110-beta, and p110-gamma. p110-alpha and p110-beta interact with SH2/SH3-domain-containing p85 adaptor proteins and with GTP-bound Ras.

NCBI Gene ID

5293

Swiss Prot

O00329

Accession Number

O00329

Host

Rabbit

Reactivity

Human

Immunogen

This PI3KCD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-114 amino acids from the N-terminal region of human PI3KCD.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=63-347

Calculated Molecular Weight

119 kDa

Fragment

Rabbit Ig

Symbol

PIK3CD

NCBI Official Name

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

NCBI Organism

Homo sapiens

Background Reference 01

Khan, N.A., et al., J. Neurovirol. 9 (6) :584-593 (2003) .

Background Reference 02

Sadhu, C., et al., J. Immunol. 170 (5) :2647-2654 (2003) .

Background Reference 03

Deregibus, M.C., et al., J. Biol. Chem. 277 (28) :25195-25202 (2002) .

Background Reference 04

Cook, J.A., et al., J. Immunol. 169 (1) :254-260 (2002) .

Other Product Names

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, PI3-kinase subunit delta, PI3K-delta, PI3Kdelta, PtdIns-3-kinase subunit delta, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta, PtdIns-3-kinase subunit p110-delta, p110delta, PIK3CD

Tested Applications

WB, IHC-P, IF

Physical Properties

Liquid

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