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PI3KC2B Antibody

Product Specifications

Background

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

NCBI Gene ID

5287

Swiss Prot

O00750

Accession Number

O00750

Host

Rabbit

Reactivity

Human

Immunogen

This PI3KC2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-150 amino acids from the N-terminal region of human PI3KC2B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

185 kDa

Fragment

Rabbit Ig

Applications Notes

For IHC-P starting dilution is: 1:10~50

Symbol

PIK3C2B

NCBI Official Name

Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta

NCBI Organism

Homo sapiens

Background Reference 01

Arcaro, A., et al., J. Biol. Chem. 273 (49) :33082-33090 (1998) .

Background Reference 02

Brown, R.A., et al., Biochem. Biophys. Res. Commun. 233 (2) :537-544 (1997) .

Other Product Names

Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta, PI3K-C2-beta, PtdIns-3-kinase C2 subunit beta, C2-PI3K, Phosphoinositide 3-kinase-C2-beta, PIK3C2B

Tested Applications

IHC-P

Physical Properties

Liquid

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