PI3KC2B Antibody
Product Specifications
Background
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
NCBI Gene ID
5287
Swiss Prot
O00750
Accession Number
O00750
Host
Rabbit
Reactivity
Human
Immunogen
This PI3KC2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-150 amino acids from the N-terminal region of human PI3KC2B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
185 kDa
Fragment
Rabbit Ig
Applications Notes
For IHC-P starting dilution is: 1:10~50
Symbol
PIK3C2B
NCBI Official Name
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
NCBI Organism
Homo sapiens
Background Reference 01
Arcaro, A., et al., J. Biol. Chem. 273 (49) :33082-33090 (1998) .
Background Reference 02
Brown, R.A., et al., Biochem. Biophys. Res. Commun. 233 (2) :537-544 (1997) .
Other Product Names
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta, PI3K-C2-beta, PtdIns-3-kinase C2 subunit beta, C2-PI3K, Phosphoinositide 3-kinase-C2-beta, PIK3C2B
Tested Applications
IHC-P
Physical Properties
Liquid
Curated Selection
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