RPS6KB2 Antibody

Product Specifications

Background

RPS6KB2 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B. Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.

NCBI Gene ID

6199

Swiss Prot

Q9UBS0

Accession Number

Q9UBS0

Host

Rabbit

Reactivity

Human

Immunogen

This RPS6KB2 antibody is generated from rabbits immunized with human RPS6KB2 recombinant protein.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

53 kDa

Fragment

Rabbit Ig

Symbol

RPS6KB2

NCBI Official Name

Ribosomal protein S6 kinase beta-2

NCBI Organism

Homo sapiens

Background Reference 01

Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (26) :16899-16903 (2002) .

Background Reference 02

Lee-Fruman, K.K., et al., Oncogene 18 (36) :5108-5114 (1999) .

Background Reference 03

Saitoh, M., et al., Biochem. Biophys. Res. Commun. 253 (2) :470-476 (1998) .

Background Reference 04

Gout, I., et al., J. Biol. Chem. 273 (46) :30061-30064 (1998) .

Other Product Names

Ribosomal protein S6 kinase beta-2, S6K-beta-2, S6K2, 70 kDa ribosomal protein S6 kinase 2, P70S6K2, p70-S6K 2, S6 kinase-related kinase, SRK, Serine/threonine-protein kinase 14B, p70 ribosomal S6 kinase beta, S6K-beta, p70 S6 kinase beta, p70 S6K-beta, p70 S6KB, p70-beta, RPS6KB2, STK14B