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CYP3A43 Antibody

Product Specifications

Background

CYP3A43 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein has a low level of testosterone hydroxylase activity. Although it bears homology to some drug-metabolizing cytochrome P450s, the protein unknown whether the enzyme is also involved in xenobiotic metabolism.

NCBI Gene ID

64816

Swiss Prot

Q9HB55

Accession Number

Q9HB55

Host

Rabbit

Reactivity

Human

Immunogen

This CYP3A43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-270 amino acids from the Central region of human CYP3A43.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

58 kDa

Fragment

Rabbit Ig

Symbol

CYP3A43

NCBI Official Name

Cytochrome P450 3A43

NCBI Organism

Homo sapiens

Background Reference 01

Domanski T.L., Finta C.Mol. Pharmacol. 59:386-392 (2001)

Background Reference 02

Westlind A., Malmebo S.Biochem. Biophys. Res. Commun. 281:1349-1355 (2001)

Background Reference 03

Cauffiez C., Lo-Guidice J.-M.Hum. Mutat. 23:101-101 (2004)

Other Product Names

Cytochrome P450 3A43, CYP3A43

Tested Applications

WB, IF, Flow

Protein ID

20137481

Physical Properties

Liquid

Frequently Asked Questions

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