CYP3A43 Antibody
Product Specifications
Background
CYP3A43 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein has a low level of testosterone hydroxylase activity. Although it bears homology to some drug-metabolizing cytochrome P450s, the protein unknown whether the enzyme is also involved in xenobiotic metabolism.
NCBI Gene ID
64816
Swiss Prot
Q9HB55
Accession Number
Q9HB55
Host
Rabbit
Reactivity
Human
Immunogen
This CYP3A43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-270 amino acids from the Central region of human CYP3A43.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
58 kDa
Fragment
Rabbit Ig
Symbol
CYP3A43
NCBI Official Name
Cytochrome P450 3A43
NCBI Organism
Homo sapiens
Background Reference 01
Domanski T.L., Finta C.Mol. Pharmacol. 59:386-392 (2001)
Background Reference 02
Westlind A., Malmebo S.Biochem. Biophys. Res. Commun. 281:1349-1355 (2001)
Background Reference 03
Cauffiez C., Lo-Guidice J.-M.Hum. Mutat. 23:101-101 (2004)
Other Product Names
Cytochrome P450 3A43, CYP3A43
Tested Applications
WB, IF, Flow
Protein ID
20137481
Physical Properties
Liquid
Curated Selection
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