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BDNF Antibody

Product Specifications

Background

BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this protein is reduced in both Alzheimer's and Huntington disease patients. This protein may play a role in the regulation of stress response and in the biology of mood disorders.

NCBI Gene ID

627

Swiss Prot

P23560

Accession Number

P23560

Host

Rabbit

Reactivity

Human

Immunogen

This BDNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-236 amino acids from the C-terminal region of human BDNF.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=63-318

Calculated Molecular Weight

28 kDa

Fragment

Rabbit Ig

Symbol

BDNF

NCBI Official Name

Brain-derived neurotrophic factor

NCBI Organism

Homo sapiens

Background Reference 01

Jiang, H., Clin. Chim. Acta 400 (1-2), 3-7 (2009)

Background Reference 02

Liu, L., Psychiatr. Genet. 18 (6), 267-274 (2008)

Background Reference 03

Dmitrzak-Weglarz, M., Pharmacogenomics (11), 1595-1603 (2008)

Other Product Names

Brain-derived neurotrophic factor, BDNF, Abrineurin, BDNF

Tested Applications

WB, IHC-P, IF, Flow

Protein ID

114900

Physical Properties

Liquid

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