BDNF Antibody
Product Specifications
Background
BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this protein is reduced in both Alzheimer's and Huntington disease patients. This protein may play a role in the regulation of stress response and in the biology of mood disorders.
NCBI Gene ID
627
Swiss Prot
P23560
Accession Number
P23560
Host
Rabbit
Reactivity
Human
Immunogen
This BDNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-236 amino acids from the C-terminal region of human BDNF.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
28 kDa
Fragment
Rabbit Ig
Symbol
BDNF
NCBI Official Name
Brain-derived neurotrophic factor
NCBI Organism
Homo sapiens
Background Reference 01
Jiang, H., Clin. Chim. Acta 400 (1-2), 3-7 (2009)
Background Reference 02
Liu, L., Psychiatr. Genet. 18 (6), 267-274 (2008)
Background Reference 03
Dmitrzak-Weglarz, M., Pharmacogenomics (11), 1595-1603 (2008)
Other Product Names
Brain-derived neurotrophic factor, BDNF, Abrineurin, BDNF
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
114900
Physical Properties
Liquid
Frequently Asked Questions
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