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FGF10 Antibody

Product Specifications

Background

FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This protein is also implicated to be a primary factor in the process of wound healing.

NCBI Gene ID

2255

Swiss Prot

O15520

Accession Number

O15520

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This FGF10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-165 amino acids from the C-terminal region of human FGF10.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

23 kDa

Fragment

Rabbit Ig

Symbol

FGF10

NCBI Official Name

Fibroblast growth factor 10

NCBI Organism

Homo sapiens

Background Reference 01

Nomura, S., Br. J. Cancer 99 (2), 305-313 (2008)

Background Reference 02

Belleudi, F., Traffic (12), 1854-1872 (2007)

Background Reference 03

Igarashi, M., J. Biol. Chem. 273 (21), 13230-13235 (1998)

Other Product Names

Fibroblast growth factor 10, FGF-10, Keratinocyte growth factor 2, FGF10

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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