RSK2 Antibody
Product Specifications
Background
RSK3 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in the gene have been associated with Coffin-Lowry syndrome (CLS) .
NCBI Gene ID
6197
Swiss Prot
P51812
Accession Number
P51812
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This RSK2 (RPS6KA3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human RSK2 (RPS6KA3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
84 kDa
Fragment
Rabbit Ig
Symbol
RPS6KA3
NCBI Official Name
Ribosomal protein S6 kinase alpha-3
NCBI Organism
Homo sapiens
Background Reference 01
Yang, X., et al., Cell 117 (3) :387-398 (2004) .
Background Reference 02
Guimiot, F., et al., Gene Expr. Patterns 4 (1) :111-114 (2004) .
Background Reference 03
Zeniou, M., et al., (er) Nucleic Acids Res. 32 (3) :1214-1223 (2004) .
Background Reference 04
Vaidyanathan, H., et al., J. Biol. Chem. 278 (34) :32367-32372 (2003) .
Other Product Names
Ribosomal protein S6 kinase alpha-3, S6K-alpha-3, 90 kDa ribosomal protein S6 kinase 3, p90-RSK 3, p90RSK3, Insulin-stimulated protein kinase 1, ISPK-1, MAP kinase-activated protein kinase 1b, MAPK-activated protein kinase 1b, MAPKAP kinase 1b, MAPKAPK-1b, Ribosomal S6 kinase 2, RSK-2, pp90RSK2, RPS6KA3, ISPK1, MAPKAPK1B, RSK2
Tested Applications
WB, IHC-P
Protein ID
1730070
Physical Properties
Liquid
Frequently Asked Questions
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