PIM1 Antibody

Product Specifications

Background

PIM1, which belongs to the Serine/Threonine protein kinase family, is thought to play a role in signal transduction in blood cells. The protooncogene PIM1 encodes a protein kinase upregulated in prostate cancer. It may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. PIM1 is expressed primarily in cells of the hematopoietic and germ line lineages.

NCBI Gene ID

5292

Swiss Prot

P11309

Accession Number

P11309

Host

Rabbit

Reactivity

Human

Immunogen

This PIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-404 amino acids from the C-terminal region of human PIM1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Symbol

PIM1

NCBI Official Name

Serine/threonine-protein kinase pim-1

NCBI Organism

Homo sapiens

Background Reference 01

Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (26) :16899-16903 (2002) . Pasqualucci, L., et al., Nature 412 (6844) :341-346 (2001) . Koike, N., et al., FEBS Lett. 467 (1) :17-21 (2000) . Reeves, R., et al., Gene 90 (2) :303-307 (1990) . Telerman, A., et al., Mol. Cell. Biol. 8 (4) :1498-1503 (1988) .