CYP11A1 Antibody

Product Specifications

Background

CYP11A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones.

NCBI Gene ID

1583

Swiss Prot

P05108

Accession Number

P05108

Host

Rabbit

Reactivity

Human

Immunogen

This CYP11A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-120 amino acids from the N-terminal region of human CYP11A1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

60 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CYP11A1

NCBI Official Name

Cholesterol side-chain cleavage enzyme, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Celhar, T., Cancer Genet. Cytogenet. 187 (1), 28-33 (2008)

Background Reference 02

Morales, A., Pancreas 37 (2), 165-169 (2008)

Background Reference 03

Shigematsu, K., Eur. J. Endocrinol. 158 (6), 867-878 (2008)

Other Product Names

Cholesterol side-chain cleavage enzyme, mitochondrial, CYPXIA1, Cholesterol desmolase, Cytochrome P450 11A1, Cytochrome P450 (scc), CYP11A1, CYP11A

Tested Applications

Protein ID

143811381

Physical Properties

Liquid

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