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CYP4F8 Antibody

Product Specifications

Background

CYP4F8 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and functions as a 19-hydroxylase of prostaglandins in seminal vesicles.

NCBI Gene ID

11283

Swiss Prot

P98187

Accession Number

P98187

Host

Rabbit

Reactivity

Human

Immunogen

This CYP4F8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-503 amino acids from the C-terminal region of human CYP4F8.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

60 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CYP4F8

NCBI Official Name

Cytochrome P450 4F8

NCBI Organism

Homo sapiens

Background Reference 01

Bylund J., Finnstroem N., Biophys. Res. Commun. 261:169-174 (1999)

Background Reference 02

Bylund J., Hidestrand M., J. Biol. Chem. 275:21844-21849 (2000)

Background Reference 03

Stark K., Toermae H., Arch. Biochem. Biophys. 409:188-196 (2003)

Background Reference 04

Stark K., Bylund J., Prostaglandins Other Lipid Mediat. 75:47-64 (2005)

Other Product Names

Cytochrome P450 4F8, CYPIVF8, CYP4F8

Tested Applications

WB

Protein ID

10719963

Physical Properties

Liquid

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