CYP2F1 Antibody
Product Specifications
Background
CYP2F1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to dehydrogenate 3-methylindole, an endogenous toxin derived from the fermentation of tryptophan, as well as xenobiotic substrates such as naphthalene and ethoxycoumarin.
NCBI Gene ID
1572
Swiss Prot
P24903
Accession Number
P24903
Host
Rabbit
Reactivity
Human
Immunogen
This CYP2F1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-424 amino acids from the C-terminal region of human CYP2F1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
56 kDa
Fragment
Rabbit Ig
Symbol
CYP2F1
NCBI Official Name
Cytochrome P450 2F1
NCBI Organism
Homo sapiens
Background Reference 01
Tournel, G., Xenobiotica 37 (12), 1433-1438 (2007)
Background Reference 02
Tournel, G., Mutat. Res. 617 (1-2), 79-89 (2007)
Background Reference 03
Nelson, D.R., Pharmacogenetics 14 (1), 1-18 (2004)
Other Product Names
Cytochrome P450 2F1, CYPIIF1, CYP2F1
Tested Applications
WB, IHC-P
Protein ID
259016202
Physical Properties
Liquid
Curated Selection
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