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CYP2F1 Antibody

Product Specifications

Background

CYP2F1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to dehydrogenate 3-methylindole, an endogenous toxin derived from the fermentation of tryptophan, as well as xenobiotic substrates such as naphthalene and ethoxycoumarin.

NCBI Gene ID

1572

Swiss Prot

P24903

Accession Number

P24903

Host

Rabbit

Reactivity

Human

Immunogen

This CYP2F1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-424 amino acids from the C-terminal region of human CYP2F1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

56 kDa

Fragment

Rabbit Ig

Symbol

CYP2F1

NCBI Official Name

Cytochrome P450 2F1

NCBI Organism

Homo sapiens

Background Reference 01

Tournel, G., Xenobiotica 37 (12), 1433-1438 (2007)

Background Reference 02

Tournel, G., Mutat. Res. 617 (1-2), 79-89 (2007)

Background Reference 03

Nelson, D.R., Pharmacogenetics 14 (1), 1-18 (2004)

Other Product Names

Cytochrome P450 2F1, CYPIIF1, CYP2F1

Tested Applications

WB, IHC-P

Protein ID

259016202

Physical Properties

Liquid

Curated Selection

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