ALDH4A1 Antibody
Product Specifications
Background
ALDH4A1 belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline.
NCBI Gene ID
8659
Swiss Prot
P30038
Accession Number
P30038
Host
Rabbit
Reactivity
Human
Immunogen
This ALDH4A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 533-561 amino acids from the C-terminal region of human ALDH4A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-260
Calculated Molecular Weight
62 kDa
Fragment
Rabbit Ig
Symbol
ALDH4A1
NCBI Official Name
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Yoon, K.A., J. Hum. Genet. 49 (3), 134-140 (2004)
Background Reference 02
Geraghty, M.T., Hum. Mol. Genet. (9), 1411-1415 (1998)
Other Product Names
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, P5C dehydrogenase, Aldehyde dehydrogenase family 4 member A1, L-glutamate gamma-semialdehyde dehydrogenase, ALDH4A1, ALDH4, P5CDH
Tested Applications
WB, IHC-P
Protein ID
62511241
Physical Properties
Liquid
Curated Selection
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