CYP2C9 Antibody

Product Specifications

Background

CYP2C9 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin.

NCBI Gene ID

1559

Swiss Prot

P11712

Accession Number

P11712

Host

Rabbit

Reactivity

Human

Immunogen

This CYP2C9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-110 amino acids from the N-terminal region of human CYP2C9.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

56 kDa

Fragment

Rabbit Ig

Symbol

CYP2C9

NCBI Official Name

Cytochrome P450 2C9

NCBI Organism

Homo sapiens

Background Reference 01

Matimba, A., Hum. Genomics (2), 169-190 (2009)

Background Reference 02

Nelson, D.R., Pharmacogenetics 14 (1), 1-18 (2004)

Other Product Names

Cytochrome P450 2C9, 11413-, (R) -limonene 6-monooxygenase, (S) -limonene 6-monooxygenase, (S) -limonene 7-monooxygenase, CYPIIC9, Cytochrome P-450MP, Cytochrome P450 MP-4, Cytochrome P450 MP-8, Cytochrome P450 PB-1, S-mephenytoin 4-hydroxylase, CYP2C9, CYP2C10