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AMPD3 Antibody

Product Specifications

Background

AMPD3 is a member of the AMP deaminase gene family. This protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. The protein is the erythrocyte (E) isoforms, whereas other family members isoforms predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency.

NCBI Gene ID

272

Swiss Prot

Q01432

Accession Number

Q01432

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This AMPD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-356 amino acids from the Central region of human AMPD3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

89 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

AMPD3

NCBI Official Name

AMP deaminase 3

NCBI Organism

Homo sapiens

Background Reference 01

Mahnke-Zizelman D.K., Eddy R.Biochim. Biophys. Acta 1306:75-92 (1996)

Background Reference 02

Yamada Y., Goto H., Wakamatsu N., Ogasawara N.Hum. Mutat. 17:78-78 (2001)

Other Product Names

AMP deaminase 3, AMP deaminase isoform E, Erythrocyte AMP deaminase, AMPD3

Tested Applications

WB

Protein ID

399033

Physical Properties

Liquid

Frequently Asked Questions

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