FKBP1B Antibody

Product Specifications

Background

FKBP1B is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. The protein is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle.

NCBI Gene ID

2281

Swiss Prot

P68106

Accession Number

P68106

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This FKBP1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human FKBP1B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Neuroscience

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Rabbit, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

12 kDa

Fragment

Rabbit Ig

Symbol

FKBP1B

NCBI Official Name

Peptidyl-prolyl cis-trans isomerase FKBP1B

NCBI Organism

Homo sapiens

Background Reference 01

Arakawa H., Nagase H.Biochem. Biophys. Res. Commun. 200:836-843 (1994)

Background Reference 02

Lam E., Martin M.M., Timerman A.P.Biol. Chem. 270:26511-26522 (1995)

Background Reference 03

Deivanayagam C.C., Carson M.Acta Crystallogr.56:266-271 (2000)

Other Product Names

Peptidyl-prolyl cis-trans isomerase FKBP1B, PPIase FKBP1B, 126 kDa FK506-binding protein, 126 kDa FKBP, FKBP-126, FK506-binding protein 1B, FKBP-1B, Immunophilin FKBP126, Rotamase, h-FKBP-12, FKBP1B, FKBP126, FKBP1L, FKBP9, OTK4