COPS3 Antibody

Product Specifications

Background

COPS3 possesses kinase activity that phosphorylates regulators involved in signal transduction. This protein phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation.

NCBI Gene ID

8533

Swiss Prot

Q9UNS2

Accession Number

Q9UNS2

Host

Rabbit

Reactivity

Human

Immunogen

This COPS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-130 amino acids from the Central region of human COPS3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

COPS3

NCBI Official Name

COP9 signalosome complex subunit 3

NCBI Organism

Homo sapiens

Background Reference 01

Henriksen J., Aagesen T.H., Maelandsmo G.M., .Oncogene 22:5358-5361 (2003)

Background Reference 02

Potocki L., Chen K.-S., Lupski J.R.Genomics 57:180-182 (1999)

Background Reference 03

Bech-Otschir D., Kraft R., Huang X., EMBO J. 20:1630-1639 (2001)

Other Product Names

COP9 signalosome complex subunit 3, SGN3, Signalosome subunit 3, JAB1-containing signalosome subunit 3, COPS3, CSN3

Tested Applications

Protein ID

55976621

Physical Properties

Liquid

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