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ACHE Antibody

Product Specifications

Background

Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. The Protein is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits.

NCBI Gene ID

43

Swiss Prot

P22303

Accession Number

P22303

Host

Rabbit

Reactivity

Human

Immunogen

This ACHE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the N-terminal region of human ACHE.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Guinea Pig

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

68 kDa

Fragment

Rabbit Ig

Symbol

ACHE

NCBI Official Name

Acetylcholinesterase

NCBI Organism

Homo sapiens

Background Reference 01

Liang, D., FEBS J. 276 (1), 94-108 (2009)

Background Reference 02

Scacchi, R., Am. J. Med. Genet.Neuropsychiatr. Genet. (2008)

Other Product Names

Acetylcholinesterase, AChE, ACHE

Tested Applications

WB, IHC-P, IF, Flow

Protein ID

113037

Physical Properties

Liquid

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