ACHE Antibody
Product Specifications
Background
Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. The Protein is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits.
NCBI Gene ID
43
Swiss Prot
P22303
Accession Number
P22303
Host
Rabbit
Reactivity
Human
Immunogen
This ACHE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the N-terminal region of human ACHE.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Guinea Pig
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-244
Calculated Molecular Weight
68 kDa
Fragment
Rabbit Ig
Symbol
ACHE
NCBI Official Name
Acetylcholinesterase
NCBI Organism
Homo sapiens
Background Reference 01
Liang, D., FEBS J. 276 (1), 94-108 (2009)
Background Reference 02
Scacchi, R., Am. J. Med. Genet.Neuropsychiatr. Genet. (2008)
Other Product Names
Acetylcholinesterase, AChE, ACHE
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
113037
Physical Properties
Liquid
Curated Selection
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