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ALDH1L1 Antibody

Product Specifications

Background

ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.

NCBI Gene ID

10840

Swiss Prot

O75891

Accession Number

O75891

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ALDH1L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 717-746 amino acids from the C-terminal region of human ALDH1L1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity, Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

99 kDa

Fragment

Rabbit Ig

Symbol

ALDH1L1

NCBI Official Name

Cytosolic 10-formyltetrahydrofolate dehydrogenase

NCBI Organism

Homo sapiens

Background Reference 01

Hosgood, H.D. III, Carcinogenesis 29 (10), 1938-1943 (2008)

Background Reference 02

Lee, K.M., Hum. Genet. 122 (5), 525-533 (2007)

Other Product Names

Cytosolic 10-formyltetrahydrofolate dehydrogenase, 10-FTHFDH, FDH, Aldehyde dehydrogenase family 1 member L1, ALDH1L1, FTHFD

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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