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MUC20 Antibody

Product Specifications

Background

This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in different individuals. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

200958

Swiss Prot

Q8N307

Accession Number

Q8N307

Host

Rabbit

Reactivity

Human

Immunogen

This MUC20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-90 amino acids from the N-terminal region of human MUC20.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

72 kDa

Fragment

Rabbit Ig

Symbol

MUC20

NCBI Official Name

Mucin-20

NCBI Organism

Homo sapiens

Background Reference 01

Li, G., Am. J. Nephrol. 26 (1), 43-49 (2006)

Background Reference 02

Suzuki, Y., Genome Res. 14 (9), 1711-1718 (2004)

Background Reference 03

Higuchi, T., Mol. Cell. Biol. 24 (17), 7456-7468 (2004)

Background Reference 04

Higuchi, T., J. Biol. Chem. 279 (3), 1968-1979 (2004)

Other Product Names

Mucin-20, MUC-20, MUC20, KIAA1359

Tested Applications

WB, IF

Protein ID

317373415

Physical Properties

Liquid

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