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APOC2 Antibody

Product Specifications

Background

APOC2 is secreted in plasma where it is a component of very low density lipoprotein. The protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in the gene encoding this protein cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.

NCBI Gene ID

344

Swiss Prot

P02655

Accession Number

P02655

Host

Rabbit

Reactivity

Human

Immunogen

This APOC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the Central region of human APOC2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

11 kDa

Fragment

Rabbit Ig

Symbol

APOC2

NCBI Official Name

Apolipoprotein C-II

NCBI Organism

Homo sapiens

Background Reference 01

Bahri, R., Lipids Health Dis 7, 46 (2008) Hegele, R.A., Dis. Markers (2), 73-80 (1991) Bengtsson-Olivecrona, G., Eur. J. Biochem. 192 (2), 515-521 (1990)

Other Product Names

Apolipoprotein C-II, Apo-CII, ApoC-II, Apolipoprotein C2, Proapolipoprotein C-II, ProapoC-II, APOC2, APC2

Tested Applications

WB, IHC-P

Protein ID

114022

Physical Properties

Liquid

Frequently Asked Questions

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