CYP3A5 Antibody
Product Specifications
Background
CYP3A5 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione.
NCBI Gene ID
1577
Swiss Prot
P20815
Accession Number
P20815
Host
Rabbit
Reactivity
Human
Immunogen
This CYP3A5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-502 amino acids from the C-terminal region of human CYP3A5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-209
Calculated Molecular Weight
57 kDa
Fragment
Rabbit Ig
Symbol
CYP3A5
NCBI Official Name
Cytochrome P450 3A5
NCBI Organism
Homo sapiens
Background Reference 01
Zencir, S., Z. Naturforsch., C, J. Biosci. 63 (9-10), 780-784 (2008)
Background Reference 02
Nelson, D.R., Pharmacogenetics 14 (1), 1-18 (2004)
Background Reference 03
Murray, G.I., FEBS Lett. 364 (1), 79-82 (1995)
Other Product Names
Cytochrome P450 3A5, CYPIIIA5, Cytochrome P450 HLp2, Cytochrome P450-PCN3, CYP3A5
Tested Applications
WB, IHC-P, IF
Protein ID
117157
Physical Properties
Liquid
Curated Selection
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