NGFB Antibody
Product Specifications
Background
NGFB is a member of the NGF-beta family. It is a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in the gene encoding NGFB have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of the gene's expression is associated with allergic rhinitis.
NCBI Gene ID
4803
Swiss Prot
P01138
Accession Number
P01138
Host
Rabbit
Reactivity
Human
Immunogen
This NGFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-115 amino acids from the Central region of human NGFB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
27 kDa
Fragment
Rabbit Ig
Symbol
NGF
NCBI Official Name
Beta-nerve growth factor
NCBI Organism
Homo sapiens
Background Reference 01
Lang, U.E., Pharmacopsychiatry 41 (5), 196-199 (2008)
Background Reference 02
Truzzi, F., J. Invest. Dermatol. 128 (8), 2031-2040 (2008)
Background Reference 03
MacGrogan, D., J. Neurochem. 59 (4), 1381-1391 (1992)
Other Product Names
Beta-nerve growth factor, Beta-NGF, NGF, NGFB
Tested Applications
WB, IHC-P, IF, Flow
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
