NTF3 Antibody

Product Specifications

Background

NTF3 is a member of the neurotrophin family that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.

NCBI Gene ID

4908

Swiss Prot

P20783

Accession Number

P20783

Host

Rabbit

Reactivity

Human

Immunogen

This NTF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-151 amino acids from the Central region of human NTF3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Pig, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

29 kDa

Fragment

Rabbit Ig

Symbol

NTF3

NCBI Official Name

Neurotrophin-3

NCBI Organism

Homo sapiens

Background Reference 01

Hossain, W.A., J. Neurosci. Res. 86 (11), 2376-2391 (2008)

Background Reference 02

Mercader, J.M., Hum. Mol. Genet. 17 (9), 1234-1244 (2008)

Background Reference 03

Kalcheim, C., Proc. Natl. Acad. Sci. U.S.A. 89 (5), 1661-1665 (1992)

Other Product Names

Neurotrophin-3, NT-3, HDNF, Nerve growth factor 2, NGF-2, Neurotrophic factor, NTF3

Tested Applications

WB, IHC-P

Protein ID

128581

Physical Properties

Liquid

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