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IPF Antibody

Product Specifications

Background

IPF is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. This nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4) .

NCBI Gene ID

3651

Swiss Prot

P52945

Accession Number

P52945

Host

Rabbit

Reactivity

Human

Immunogen

This IPF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-72 amino acids from human IPF.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=63-178

Calculated Molecular Weight

31 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PDX1

NCBI Official Name

Pancreas/duodenum homeobox protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Ma, J., Carcinogenesis 29 (7), 1327-1333 (2008)

Background Reference 02

Watada, H., Biochem. Biophys. Res. Commun. 229 (3), 746-751 (1996)

Other Product Names

Pancreas/duodenum homeobox protein 1, PDX-1, Glucose-sensitive factor, GSF, Insulin promoter factor 1, IPF-1, Insulin upstream factor 1, IUF-1, Islet/duodenum homeobox-1, IDX-1, Somatostatin-transactivating factor 1, STF-1, PDX1, IPF1, STF1

Tested Applications

WB

Protein ID

1708540

Physical Properties

Liquid

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