PUM2 Antibody

Product Specifications

Background

PUM2 is a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts.

NCBI Gene ID

23369

Swiss Prot

Q8TB72

Accession Number

Q8TB72

Host

Rabbit

Reactivity

Human

Immunogen

This PUM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-189 amino acids from human PUM2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

114 kDa

Fragment

Rabbit Ig

Symbol

PUM2

NCBI Official Name

Pumilio homolog 2

NCBI Organism

Homo sapiens

Background Reference 01

Kusz, K., Mol. Reprod. Dev. 74 (6), 795-799 (2007)

Background Reference 02

Spik, A., Reprod BiolSUPPL 1, 37-42 (2006)

Background Reference 03

Moore, F.L., Proc. Natl. Acad. Sci. U.S.A. 100 (2), 538-543 (2003)

Other Product Names

Pumilio homolog 2, Pumilio-2, PUM2, KIAA0235, PUMH2

Tested Applications

WB, IHC-P, Flow

Protein ID

41688714

Physical Properties

Liquid

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