TNK1 Antibody

Product Specifications

Background

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

NCBI Gene ID

8711

Swiss Prot

Q13470

Accession Number

Q13470

Host

Rabbit

Reactivity

Human

Immunogen

This TNK1 antibody is generated from rabbits immunized with TNK1 recombinant protein.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

72 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TNK1

NCBI Official Name

Non-receptor tyrosine-protein kinase TNK1

NCBI Organism

Homo sapiens

Background Reference 01

Blume-Jensen P, et al. Nature 2001. 411: 355.

Background Reference 02

Cantrell D, J. Cell Sci. 2001. 114: 1439.

Background Reference 03

JhiangOncogene 2000. 19: 5590.

Background Reference 04

Manning G, et al. Science 2002. 298: 1912.

Other Product Names

Non-receptor tyrosine-protein kinase TNK1, CD38 negative kinase 1, TNK1 {ECO:0000312|EMBL:AAC994121}

Tested Applications

Protein ID

116242821

Physical Properties

Liquid

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