LYN Antibody

Product Specifications

Background

Lyn is a protein tyrosine kinase which is important in cellular signaling. It contains an SH2 and SH3 domain and has been found to be cleaved after activation of caspases in apoptosis.

NCBI Gene ID

4067

Swiss Prot

P07948

Accession Number

P07948

Host

Rabbit

Reactivity

Human

Immunogen

This LYN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-62 amino acids from the N-terminal region of human LYN.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

59 kDa

Fragment

Rabbit Ig

Symbol

LYN

NCBI Official Name

Tyrosine-protein kinase Lyn

NCBI Organism

Homo sapiens

Background Reference 01

Baran, C.P., et al., J. Biol. Chem. 278 (40) :38628-38636 (2003) . Donato, N.J., et al., Blood 101 (2) :690-698 (2003) . Santini, V., et al., Haematologica 87 (12) :1242-1247 (2002) . Harashima, A., et al., Blood 100 (13) :4440-4445 (2002) . Ren, X., et al., Cancer Biol. Ther. 1 (6) :703-708 (2002) .

Other Product Names

Tyrosine-protein kinase Lyn, Lck/Yes-related novel protein tyrosine kinase, V-yes-1 Yamaguchi sarcoma viral related oncogene homolog, p53Lyn, p56Lyn, LYN, JTK8