LYN Antibody
Product Specifications
Background
Lyn is a protein tyrosine kinase which is important in cellular signaling. It contains an SH2 and SH3 domain and has been found to be cleaved after activation of caspases in apoptosis.
NCBI Gene ID
4067
Swiss Prot
P07948
Accession Number
P07948
Host
Rabbit
Reactivity
Human
Immunogen
This LYN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-62 amino acids from the N-terminal region of human LYN.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-165
Calculated Molecular Weight
59 kDa
Fragment
Rabbit Ig
Symbol
LYN
NCBI Official Name
Tyrosine-protein kinase Lyn
NCBI Organism
Homo sapiens
Background Reference 01
Baran, C.P., et al., J. Biol. Chem. 278 (40) :38628-38636 (2003) . Donato, N.J., et al., Blood 101 (2) :690-698 (2003) . Santini, V., et al., Haematologica 87 (12) :1242-1247 (2002) . Harashima, A., et al., Blood 100 (13) :4440-4445 (2002) . Ren, X., et al., Cancer Biol. Ther. 1 (6) :703-708 (2002) .
Other Product Names
Tyrosine-protein kinase Lyn, Lck/Yes-related novel protein tyrosine kinase, V-yes-1 Yamaguchi sarcoma viral related oncogene homolog, p53Lyn, p56Lyn, LYN, JTK8
Tested Applications
WB, IHC-P, Flow
Protein ID
125480
Physical Properties
Liquid
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