FYN Antibody

Product Specifications

Background

FYN is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein.

NCBI Gene ID

2534

Swiss Prot

P06241

Accession Number

P06241

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This FYN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-43 amino acids from the N-terminal region of human FYN.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

61 kDa

Fragment

Rabbit Ig

Symbol

FYN

NCBI Official Name

Tyrosine-protein kinase Fyn

NCBI Organism

Homo sapiens

Background Reference 01

Taniguchi, S., et al., Biochem. Biophys. Res. Commun. 306 (1) :151-155 (2003) . Chan, B., et al., Nat. Cell Biol. 5 (2) :155-160 (2003) . Goldsmith, J.F., et al., Biochem. Biophys. Res. Commun. 298 (4) :501-504 (2002) . Freund, C., et al., EMBO J. 21 (22) :5985-5995 (2002) . Parravicini, V., et al., Nat. Immunol. 3 (8) :741-748 (2002) .