BMX Antibody

Product Specifications

Background

Tyrosine kinases are either receptor molecules, which contain transmembrane and extracellular domains, or nonreceptor proteins, which are located intracellularly. One family of nonreceptor TKs includes the genes TEC (MIM 600583), TXK (MIM 600058), ITK (MIM 186973), and BTK (MIM 300300) . All of these proteins are homologs of the Drosophila Src28 TK and contain an SH3 and SH2 domain upstream of the TK domain.[supplied by OMIM]

NCBI Gene ID

660

Swiss Prot

P51813

Accession Number

P51813

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This BMX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-242 amino acids from the Central region of human BMX.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

78 kDa

Fragment

Rabbit Ig

Symbol

BMX

NCBI Official Name

Cytoplasmic tyrosine-protein kinase BMX

NCBI Organism

Homo sapiens

Background Reference 01

Pan, S., et al., Mol. Cell. Biol. 22 (21) :7512-7523 (2002) .

Background Reference 02

Qiu, Y., et al., Proc. Natl. Acad. Sci. U.S.A. 95 (7) :3644-3649 (1998) .

Background Reference 03

Tamagnone, L., et al., Oncogene 9 (12) :3683-3688 (1994) .

Other Product Names

Cytoplasmic tyrosine-protein kinase BMX, Bone marrow tyrosine kinase gene in chromosome X protein, Epithelial and endothelial tyrosine kinase, ETK, NTK38, BMX