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TYRO3 Antibody

Product Specifications

Background

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

NCBI Gene ID

7301

Swiss Prot

Q06418

Accession Number

Q06418

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This TYRO3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 842-873 amino acids from the C-terminal region of human TYRO3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology, Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

97 kDa

Fragment

Rabbit Ig

Symbol

TYRO3

NCBI Official Name

Tyrosine-protein kinase receptor TYRO3

NCBI Organism

Homo sapiens

Background Reference 01

Dai, W., et al., Oncogene 9 (3) :975-979 (1994) .

Background Reference 02

Richard, I., et al., Genomics 23 (3) :619-627 (1994) .

Background Reference 03

Mark, M.R., et al., J. Biol. Chem. 269 (14) :10720-10728 (1994) .

Background Reference 04

Crosier, K.E., et al., Growth Factors 11 (2) :137-144 (1994) .

Other Product Names

Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase BYK, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE, Tyrosine-protein kinase SKY, Tyrosine-protein kinase TIF, TYRO3, BYK, DTK, RSE, SKY, TIF

Tested Applications

WB, IHC-P

Protein ID

1717829

Physical Properties

Liquid

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