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PDGFRB Antibody

Product Specifications

Background

PDGFRB is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides.

NCBI Gene ID

5159

Swiss Prot

P09619

Accession Number

P09619

Host

Rabbit

Reactivity

Human

Immunogen

This PDGFRB antibody is generated from rabbits immunized with human recombinant PDGFRB protein.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=63-122

Calculated Molecular Weight

124 kDa

Fragment

Rabbit Ig

Symbol

PDGFRB

NCBI Official Name

Platelet-derived growth factor receptor beta

NCBI Organism

Homo sapiens

Background Reference 01

Wu, H., et al., J. Biol. Chem. 278 (42) :40425-40428 (2003) .

Background Reference 02

Whiteman, E.L., et al., Endocrinology 144 (9) :3811-3820 (2003) .

Background Reference 03

Uren, A., et al., Oncogene 22 (15) :2334-2342 (2003) .

Background Reference 04

Steer, E.J., et al., Acta Haematol. 107 (2) :113-122 (2002) .

Other Product Names

Platelet-derived growth factor receptor beta, PDGF-R-beta, PDGFR-beta, Beta platelet-derived growth factor receptor, Beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, Platelet-derived growth factor receptor 1, PDGFR-1, CD140b, PDGFRB, PDGFR, PDGFR1

Tested Applications

WB, IHC-P, IF

Protein ID

129890

Physical Properties

Liquid

Curated Selection

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