KIT Antibody
Product Specifications
Background
KIT is the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor) . Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.
NCBI Gene ID
3815
Swiss Prot
P10721
Accession Number
P10721
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This KIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the N-terminal region of human KIT.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-107
Calculated Molecular Weight
110 kDa
Fragment
Rabbit Ig
Symbol
KIT
NCBI Official Name
Mast/stem cell growth factor receptor Kit
NCBI Organism
Homo sapiens
Background Reference 01
Wardelmann, E., et al., Int. J. Cancer 106 (6) :887-895 (2003) . Lennartsson, J., et al., Exp. Cell Res. 288 (1) :110-118 (2003) . Sakuma, Y., et al., Cancer Sci 94 (6) :486-491 (2003) . Araki, K., et al., Lung Cancer 40 (2) :173-180 (2003) . Voytyuk, O., et al., J. Biol. Chem. 278 (11) :9159-9166 (2003) .
Other Product Names
Mast/stem cell growth factor receptor Kit, SCFR, Piebald trait protein, PBT, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, p145 c-kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, CD117, KIT, SCFR
Tested Applications
WB, IHC-P, Flow
Protein ID
125472
Physical Properties
Liquid
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