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ILK Antibody

Product Specifications

Background

Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK is a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.

NCBI Gene ID

3611

Swiss Prot

Q13418

Accession Number

Q13418

Host

Rabbit

Reactivity

Human

Immunogen

This ILK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from human ILK.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=63-101

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Symbol

ILK

NCBI Official Name

Integrin-linked protein kinase

NCBI Organism

Homo sapiens

Background Reference 01

Li, Y., et al., J. Clin. Invest. 112 (4) :503-516 (2003) .

Background Reference 02

Troussard, A.A., et al., J. Biol. Chem. 278 (25) :22374-22378 (2003) .

Background Reference 03

Marotta, A., et al., Br. J. Cancer 88 (11) :1755-1762 (2003) .

Background Reference 04

Cordes, N., et al., Br. J. Cancer 88 (9) :1470-1479 (2003) .

Other Product Names

Integrin-linked protein kinase, 59 kDa serine/threonine-protein kinase, ILK-1, ILK-2, p59ILK, ILK, ILK1, ILK2

Tested Applications

WB, IHC-P

Protein ID

9973397

Physical Properties

Liquid

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