FUCA2 Antibody
Product Specifications
Background
Alpha-L-fucosidase catalyzes the hydrolysis of terminal alpha-L-fucosidase linkages in glycosphingolipids and glycoproteins. At least 2 separate polymorphic alpha-L-fucosidases are recognized in man. The FUCA2 locus regulates the level of alpha-fucosidase in plasma and fibroblasts but not in leukocytes. In fucosidosis, deficiency of alpha-L-fucosidase is found in both plasma and leukocytes.
NCBI Gene ID
2519
Swiss Prot
Q9BTY2
Accession Number
Q9BTY2
Host
Rabbit
Reactivity
Human
Immunogen
This FUCA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the N-terminal region of human FUCA2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
54 kDa
Fragment
Rabbit Ig
Symbol
FUCA2
NCBI Official Name
Plasma alpha-L-fucosidase
NCBI Organism
Homo sapiens
Background Reference 01
Clark, H.F., et al., Genome Res. 13 (10) :2265-2270 (2003) .
Background Reference 02
Eiberg, H., et al., Clin. Genet. 26 (1) :23-29 (1984) .
Other Product Names
Plasma alpha-L-fucosidase, Alpha-L-fucoside fucohydrolase 2, Alpha-L-fucosidase 2, FUCA2
Tested Applications
WB, IHC-P
Protein ID
254763296
Physical Properties
Liquid
Curated Selection
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