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FUCA2 Antibody

Product Specifications

Background

Alpha-L-fucosidase catalyzes the hydrolysis of terminal alpha-L-fucosidase linkages in glycosphingolipids and glycoproteins. At least 2 separate polymorphic alpha-L-fucosidases are recognized in man. The FUCA2 locus regulates the level of alpha-fucosidase in plasma and fibroblasts but not in leukocytes. In fucosidosis, deficiency of alpha-L-fucosidase is found in both plasma and leukocytes.

NCBI Gene ID

2519

Swiss Prot

Q9BTY2

Accession Number

Q9BTY2

Host

Rabbit

Reactivity

Human

Immunogen

This FUCA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the N-terminal region of human FUCA2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Symbol

FUCA2

NCBI Official Name

Plasma alpha-L-fucosidase

NCBI Organism

Homo sapiens

Background Reference 01

Clark, H.F., et al., Genome Res. 13 (10) :2265-2270 (2003) .

Background Reference 02

Eiberg, H., et al., Clin. Genet. 26 (1) :23-29 (1984) .

Other Product Names

Plasma alpha-L-fucosidase, Alpha-L-fucoside fucohydrolase 2, Alpha-L-fucosidase 2, FUCA2

Tested Applications

WB, IHC-P

Protein ID

254763296

Physical Properties

Liquid

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