VEGFR2 Antibody

Product Specifications

Background

KDR (FLK1) is a receptor for VEGF or VEGFC. This protein has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.

NCBI Gene ID

3791

Swiss Prot

P35968

Accession Number

P35968

Host

Rabbit

Reactivity

Human

Immunogen

This VEGFR2 (FLK1/KDR) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1326-1356 amino acids from the C-terminal region of human VEGFR2 (FLK1/KDR) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology, Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

152 kDa

Fragment

Rabbit Ig

Symbol

KDR

NCBI Official Name

Vascular endothelial growth factor receptor 2

NCBI Organism

Homo sapiens

Background Reference 01

Yilmaz, A., et al., Biochem. Biophys. Res. Commun. 306 (3) :730-736 (2003) .

Background Reference 02

Zeng, H., et al., J. Biol. Chem. 278 (23) :20738-20745 (2003) .

Background Reference 03

Kiba, A., et al., J. Biol. Chem. 278 (15) :13453-13461 (2003) .

Background Reference 04

Elvert, G., et al., J. Biol. Chem. 278 (9) :7520-7530 (2003) .

Other Product Names

Vascular endothelial growth factor receptor 2, VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, KDR, Protein-tyrosine kinase receptor flk-1, CD309, KDR, FLK1, VEGFR2