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XPOT Antibody

Product Specifications

Background

XPOT is a protein belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm. Translocation of tRNA to the cytoplasm occurs once exportin has bound both tRNA and GTP-bound RAN.

NCBI Gene ID

11260

Swiss Prot

O43592

Accession Number

O43592

Host

Rabbit

Reactivity

Human

Immunogen

This XPOT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-166 amino acids from the N-terminal region of human XPOT.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

110 kDa

Fragment

Rabbit Ig

Symbol

XPOT

NCBI Official Name

Exportin-T

NCBI Organism

Homo sapiens

Background Reference 01

Li, S.RNA Biol (4), 145-149 (2006)

Background Reference 02

Suzuki, T., Biomed. Res. 27 (2), 89-92 (2006)

Background Reference 03

Kuersten, S., Mol. Cell. Biol. 22 (16), 5708-5720 (2002)

Other Product Names

Exportin-T, Exportin (tRNA), tRNA exportin, XPOT

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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