EphA7 Antibody

Product Specifications

Background

EphA7 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.[1]

NCBI Gene ID

2045

Swiss Prot

Q15375

Accession Number

Q15375

Host

Rabbit

Reactivity

Human

Immunogen

This EphA7 antibody is generated from rabbits immunized with recombinant human EphA7 protein.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

112 kDa

Fragment

Rabbit Ig

Symbol

EPHA7

NCBI Official Name

Ephrin type-A receptor 7

NCBI Organism

Homo sapiens

Background Reference 01

Wilkinson, D.G., Nat Rev Neurosci 2 (3) :155-164 (2001) . Xu, Q., et al., Philos. Trans. R. Soc. Lond., B, Biol. Sci. 355 (1399) :993-1002 (2000) . Holder, N., et al., Development 126 (10) :2033-2044 (1999) . Zhou, R., Pharmacol. Ther. 77 (3) :151-181 (1998) . Fox, G.M., et al., Oncogene 10 (5) :897-905 (1995) .