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CSF1R Antibody

Product Specifications

Background

CSF1R is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases.

NCBI Gene ID

1436

Swiss Prot

P07333

Accession Number

P07333

Host

Rabbit

Reactivity

Human

Immunogen

This CSF1R antibody is generated from rabbits immunized with CSF1R recombinant protein.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=63-033

Calculated Molecular Weight

108 kDa

Fragment

Rabbit Ig

Symbol

CSF1R

NCBI Official Name

Macrophage colony-stimulating factor 1 receptor

NCBI Organism

Homo sapiens

Background Reference 01

Guey, L.T., et.al., Eur. Urol. 57 (2), 283-292 (2010)

Background Reference 02

Wooten, E.C., et.al., PLoS ONE (1), E8830 (2010)

Background Reference 03

Hosgood, H.D. III, et.al., Respir Med 103 (12), 1866-1870 (2009)

Other Product Names

Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor, CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms, CD115, CSF1R, FMS

Tested Applications

WB, IF, Flow

Protein ID

547770

Physical Properties

Liquid

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