AXL Antibody

Product Specifications

Background

AXL, a member of the AXL/UFO subfamily of Tyr protein kinases, may function as a signal transducer between specific cell types of mesodermal origin. This Type I membrane protein has transforming potential in patients with chronic myeloproliferative disorder or chronic myelocytic leukemia. The protein contains 2 putative fibronectin type III domains and 2 putative immunoglobulin-like C2-type domains.

NCBI Gene ID

558

Swiss Prot

P30530

Accession Number

P30530

Host

Rabbit

Reactivity

Human

Immunogen

This AXL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 863-894 amino acids from the C-terminal region of human AXL.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

98 kDa

Fragment

Rabbit Ig

Symbol

AXL

NCBI Official Name

Tyrosine-protein kinase receptor UFO

NCBI Organism

Homo sapiens

Background Reference 01

Lee, S.T., et al., Oncogene 8 (12) :3403-3410 (1993) .

Background Reference 02

Janssen, J.W., et al., Oncogene 6 (11) :2113-2120 (1991) .

Background Reference 03

O'Bryan, J.P., et al., Mol. Cell. Biol. 11 (10) :5016-5031 (1991) .

Background Reference 04

Partanen, J., et al., Proc. Natl. Acad. Sci. U.S.A. 87 (22) :8913-8917 (1990) .

Other Product Names

Tyrosine-protein kinase receptor UFO, AXL oncogene, AXL, UFO

Tested Applications

WB, IHC-P

Protein ID

239938818

Physical Properties

Liquid

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