CLIC1 Antibody
Product Specifications
Background
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
NCBI Gene ID
1192
Swiss Prot
O00299
Accession Number
O00299
Host
Rabbit
Reactivity
Human
Immunogen
This CLIC1 antibody is generated from rabbits immunized with a recombinant human CLIC1 protein.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-017
Calculated Molecular Weight
27 kDa
Fragment
Rabbit Ig
Symbol
CLIC1
NCBI Official Name
Chloride intracellular channel protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Singh, H., FEBS J. 274 (24), 6306-6316 (2007)
Background Reference 02
Ulmasov, B., (er) BMC Cell Biol. 8, (2007)
Background Reference 03
Edwards, J.C., J. Membr. Biol. 213 (1), 39-46 (2006)
Other Product Names
Chloride intracellular channel protein 1, Chloride channel ABP, Nuclear chloride ion channel 27, NCC27, Regulatory nuclear chloride ion channel protein, hRNCC, CLIC1, G6, NCC27
Tested Applications
WB, IHC-P
Physical Properties
Liquid
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