CLIC1 Antibody

Product Specifications

Background

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.

NCBI Gene ID

1192

Swiss Prot

O00299

Accession Number

O00299

Host

Rabbit

Reactivity

Human

Immunogen

This CLIC1 antibody is generated from rabbits immunized with a recombinant human CLIC1 protein.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

27 kDa

Fragment

Rabbit Ig

Symbol

CLIC1

NCBI Official Name

Chloride intracellular channel protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Singh, H., FEBS J. 274 (24), 6306-6316 (2007)

Background Reference 02

Ulmasov, B., (er) BMC Cell Biol. 8, (2007)

Background Reference 03

Edwards, J.C., J. Membr. Biol. 213 (1), 39-46 (2006)

Other Product Names

Chloride intracellular channel protein 1, Chloride channel ABP, Nuclear chloride ion channel 27, NCC27, Regulatory nuclear chloride ion channel protein, hRNCC, CLIC1, G6, NCC27