SOD2 Antibody

Product Specifications

Background

SOD2 is a member of the iron/manganese superoxide dismutase family. It is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.

NCBI Gene ID

6648

Swiss Prot

P04179

Accession Number

P04179

Host

Rabbit

Reactivity

Human

Immunogen

This SOD2 antibody is generated from rabbits immunized with human recombinant SD protein.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity, Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

25 kDa

Fragment

Rabbit Ig

Symbol

SOD2

NCBI Official Name

Superoxide dismutase [Mn], mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Fabre, E.E., Am. J. Clin. Nutr. 87 (5), 1504-1512 (2008) Kaewpila, S., Cancer Res. 68 (8), 2781-2788 (2008) Flekac, M., (er) BMC Med. Genet. 9, 30 (2008)